| Total Synthesis of Three New Dihydrostilbenes from Bulbophllum odoratissimum |
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| 作者姓名： | Jin Guang LIN Wei Ge ZHANG Rui ZHAO Ze Yu NIU Kai BAO Dai Lin LIU Nai Li WANG Xin Shen YAO |
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| 作者单位： | Jin Guang LIN1，Wei Ge ZHANG1，2?，Rui ZHAO1，Ze Yu NIU1，Kai BAO1，Dai Lin LIU2，Nai Li WANG2，Xin Shen YAO2* 1School of Pharmaceutical Engineering，Shenyang Pharmaceutical University，Shenyang 110016 2The Research Center of Traditional Chinese Medicines and Natural Products，Research Institute of Tsinghua University，Shenzhen 518057 |
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| 基金项目： | We gratefully acknowledge Dr. Guo Liang CHEN, Shenyang Pharmaceutical University, for valuable discussion. |
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| 摘 要： | Natural stilbenoids are presently well known by their various kinds of bioactivity, such as antitumor, anti-inflammatory and platelet antiaggregation1. In our previous studies of naturally-occurring cytotoxic agents present in traditional Chinese medicine…
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| 关 键 词： | 总合成 二氢基均二苯代乙烯 抗癌活性 天然化合物 中药 分离 提取 Bulbophllum odoratissimum |
| 收稿时间： | 2005-07-20 |
Total Synthesis of Three New Dihydrostilbenes from Bulbophllum odoratissimum |
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| Jin Guang LIN Wei Ge ZHANG Rui ZHAO Ze Yu NIU Kai BAO Dai Lin LIU Nai Li WANG Xin Shen YAO.Total Synthesis of Three New Dihydrostilbenes from Bulbophllum odoratissimum[J].Chinese Chemical Letters,2006,17(3):307-309. |
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| Authors: | Jin Guang LIN Wei Ge ZHANG Rui ZHAO Ze Yu NIU Kai BAO Dai Lin LIU Nai Li WANG Xin Shen YAO |
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| Abstract: | A total synthesis of three new dihydrostilbenes, 1, 2 and 3, which were isolated from Bulbophyllum odoratissimum Lindl. with significant cytotoxicity toward human cancer cell lines, was developed via Horner reaction etc. The natural products 1, 2 and 3 were obtained in 5.8%, 6.6% and 5.9%, respectively. |
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| Keywords: | Dihydrostilbene total synthesis Bulbophyllum odoratissimum Lindl |
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