Palladium-catalyzed diastereoselective synthesis of homoaldol equivalent products |
| |
| Authors: | Yoshikazu Horino Miki Sugata Tetsu Sugita Ataru Aimono Hitoshi Abe |
| |
| Institution: | Department of Applied Chemistry, Graduate School of Science and Engineering, University of Toyama, Gofuku, Toyama 930-8555, Japan |
| |
| Abstract: | A palladium-catalyzed reaction of easily accessible 3-(pinacolatoboryl)allyl acetates and aldehydes provides facile access to synthetically useful homoaldol equivalent products with high diastereoselectivity. The reaction presumably proceeds via allylation of aldehydes with α-acetoxy allylboronates that produced in situ by reductive elimination from allylic gem-palladium/boryl intermediates. |
| |
| Keywords: | Allylation Homoaldol equivalent reaction Palladium catalysis Allylpalladium |
| 本文献已被 ScienceDirect 等数据库收录！ |
