| N,N-Di-isopropyl-O,O-Di-p-methoxybenzylphosphoramidite——A New Phosphorylating Reagent |
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| 作者姓名： | Shoichirol OZAKI Ai You HAO Xiang Zheng KONG Da Xing ZHENG |
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| 作者单位： | Department of Chemistry，Shandong University，Jinan 250100 |
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| 摘 要： | Thedibenzyldiisopropylphosphoramidite"',whichcouldbecleavedbyreduction(hydrogenolysis),isaveryusefulreagentforthephosphorylationofhydroxygroupespeciallyvicinalhydroxygroup.Itisusedveryoftenforthesynthesisofnucleotideandmyo-inositolpolyphosphates.However,itcannotbeusedforthephosphorylationofthecompoundshavinganolefinicgroupwhichwouldalsobereducedtoparaffininthereductioncleavingofthebenZylgroup.Now,WereportthesynthesisofanewphosphorylatingreagentN,N-di-isopropyl-O,O-di-P-methox1.Sincep-methox…
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