Hypocholesterolemic agent compactin. an alternative diels-alder strategy for the synthesis of the hexahydronaphthalene portion |
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Authors: | Raymond L. Funk Craig J. Mossman Wayne E. Zeller |
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Affiliation: | Department of Chemistry University of Nebraska-Lincoln Lincoln, Nebraska 68588 U.S.A. |
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Abstract: | The synthesis of the hexahydronaphthalene segment (4) of compactin (1) has been accomplished in a short sequence (8 steps from 9) featuring the intramolecular Diels-Alder cycloaddition of 7b. |
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