Synthetic studies related to compactin and mevinolin: A new synthesis of the lactone system. |
| |
| Authors: | Marek Majewski Derrick L.J. Clive Paul C. Anderson |
| |
| Affiliation: | Department of Chemistry, University of Alberta, Edmonton, Alberta T6G 2G2, Canada |
| |
| Abstract: | (S)-Malic acid diethyl ester was converted into a precursor of the lactonic portion of compactin and mevinolin. The substance was coupled with benzyl -tolyl sulfone and elaborated into the chiral lactone system of the natural products. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
