New convenient one-step synthesis of 4-arylphthalaz-1 -ones |
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| Authors: | M. Fekry Ismail F.A. El-Bassiouny H.A. Younes |
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| Affiliation: | Chemistry Department, Faculty of Science, Ain Shams University, Abbassia, Cairo A.R. Egypt |
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| Abstract: | 4-Arylphthalaz-1-ones (2a–e) are prepared by the hitherto unknown reaction of N-aminophthalimide (1) with aromatic hydrocarbons under Friedel-Crafts conditions. The reaction of N-aminophthalimide with Grignard reagents presents another convenient method for the synthesis of 4-alkyl or 4-arylphthalaz-1-ones. |
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