The synthesis of a 3-diazobicyclo[2.2.1]Heptan-2-one inhibitor of thromboxane a2 synthetase |
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Authors: | Jerry L Adams Brian W Metcalf |
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Institution: | Merrell Dow Research Institute Merrell Dow Pharmaceuticals Inc. 2110 East Galbraith Road Cincinnati, Ohio 45215 U.S.A. |
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Abstract: | The synthesis of a PGH2 analog 5-(2(Z), 6-(1E)-3-diazo-5-(7-hydroxy-2-heptenyl)-6-(3-hydroxy-1-octenyl)bicyclo2.2.1]heptan-2-one 2 is described. |
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