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The synthesis of a 3-diazobicyclo[2.2.1]Heptan-2-one inhibitor of thromboxane a2 synthetase
Authors:Jerry L Adams  Brian W Metcalf
Institution:Merrell Dow Research Institute Merrell Dow Pharmaceuticals Inc. 2110 East Galbraith Road Cincinnati, Ohio 45215 U.S.A.
Abstract:The synthesis of a PGH2 analog 5-endo(2(Z), 6-exo(1E)-3-diazo-5-(7-hydroxy-2-heptenyl)-6-(3-hydroxy-1-octenyl)bicyclo2.2.1]heptan-2-one 2 is described.
Keywords:
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