The anaerobic degradation of deoxycholic acid by PSEUDOMONAS SP. NCIB 10590 |
| |
Authors: | RW Owen AN Mason RF Bilton |
| |
Institution: | Department of Chemistry and Biochemistry, Liverpool Polytechnic, Liverpool England |
| |
Abstract: | The anaerobic metabolism of deoxycholic acid by Pseudomonas sp. NCIB 10590 was studied. The metabolic pathway was similar to that operating under aerobic conditions with 12β-hydroxyandrosta-1,4-dien-3,17-dione as the major neutral product an metabolites which are not produced during aerobic metabolism were isolated and evidence is presented for the following structures: 9α-hydroxyandrost-1-en-3,17-dione, 12α,17)β-dihydroxyandrosta-1,4-dien-3-one; 3β,12β-dihydroxy-5β-androstan-17-one an formation and significance of the phenolic secosteroid is discussed. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |
|