Synthesis of protected derivatives of O-phosphotyrosine incorporation in a heptapeptide |
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| Authors: | R.M. Valerio P.F. Alewood R.B. Johns B.E. Kemp |
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| Affiliation: | Department of Chemistry University of Melbourne and Howard Florey Institute of Experimental Physiology and Medicine, University of Melbourne, Parkville, 3052, Victoria, Australia |
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| Abstract: | The solid phase synthesis of the phosphopeptide Leu-Arg-Arg-Ala-Tyr(P)-Leu-Gly is reported via the stepwise incorporation of the protected phosphoamino acid Nα -tert-butyloxycarbonyl-O-dimethyl-phosphono-L-tyrosine. |
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