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Synthesis of 5S,12S - diHETE (LTBx) |
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| Authors: | Julian Adams Yves Leblanc Joshua Rokach |
| Affiliation: | Merck Frosst Canada Inc. P.O. Box 1005,Pointe Claire/Dorval, Quebec,Canada H9R 4P8 |
| Abstract: | The total synthesis of 5S, 12S-diHETE (LTBx) was completed. The Wittig reaction of phosphorane 8 and chiral aldehyde 9 provided the key step to from the C-20 chain. |
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