|
|||||
|
|
The efficient synthesis of chiral key intermediates for monobactam antibiotics |
|
| Authors: | Atsushi Nishida Masakatsu Shibasaki Shiro Ikegami |
| Affiliation: | Faculty of Pharmaceutical Sciences, Teikyo University, Sagamiko, Kanagawa 199-01, Japan |
| Abstract: | Chemical asymmetric syntheses of the key intermediates (4,6,8) for the synthesis of monobactam antibiotics (SQ 26776 (azthreonam), sulfazecin, and SQ 26180) are accomplished from (±)-4-phenylsulfonyl-2-azetidinone. |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ | |