(±)-Nuevamine,an isoindoloisoquinoline alkaloid,and (±)-lennoxamine,an isoindolobenzazepine |
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| Authors: | Emir Valencia Alan J. Freyer Maurice Shamma Victor Fajardo |
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| Affiliation: | Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, USA;Departamento de Química, Petroleo y Petroquímica, Universidad de Magallanes, Punta Arenas, Chile |
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| Abstract: | Hook (Berberidaceae) has yielded the lactams (±)-nuevamine (7) and (±)-lennoxamine (8). Nuevamine is the first known isoindoloisoquinoline alkaloid, while lennoxamine is an isoindolobenzazepine structurally related to (±)-chilenine (3). |
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