An efficient carbapenem synthesis via an intramolecular Wittig reaction of new trialkoxyphosphorane-thiolesters |
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| Authors: | Akira Yoshida Yawara Tajima Noriko Takeda Sadao Oida |
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| Affiliation: | Chemical Research Laboratories, Sankyo Co., Ltd., Hiromachi, Shinagawa-ku, Tokyo, 140, Japan |
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| Abstract: | New trialkoxyphosphorane-thiolesters 10, obtained by reaction of oxalimides 9 with trialkyl phosphite, were efficiently cyclized by an intramolecular Wittig reaction to give carbapenems 11. |
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