(S)-tetrahydroprotoberberine oxidase the final enzyme in protoberberine biosynthesis |
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Authors: | M Amann N Nagakura MH Zenk |
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Institution: | 1. Kobe Women''s College of Pharmacy, Kobe 658, Japan |
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Abstract: | A new flavin enzyme has been discovered which in the presence of O2 catalyses the oxidation of (S)-tetrahydro-protoberberines to protoberberines via the intermediate 7,14-dehydroberberinium. |
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