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Synthesis of 2-isopropylfuro(2,3-b)quinolines-a new synthesis of (±)-lunacrine, (±)-lunasine and (±)-demethoxylunacrine
Authors:M. Ramesh  P.S. Mohan  P. Shanmugam
Affiliation:Department of Chemistry, Bharathiar University, Coimbatore - 641 046, India
Abstract:A new and convenient synthesis of 2-isopropylfuro-(2,3-b)quinolines (4) from 3-(3-methylbut-1-enyl)-2-quinolones (2) is described. A neat synthesis of the alkaloids (±)-lunacrine (1a), (±)-lunasine (12a) and (±)-demethoxylunacrine (1b) is also reported.
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