Keramadine,a novel antagonist of serotonergic receptors isolated from the okinawan sea sponge Agelas sp. |
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| Authors: | Hideshi Nakamura,Yasushi Ohizumi,Jun&#x ichi Kobayashi,Yoshimasa Hirata |
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| Affiliation: | Mitsubishi-Kasei Institute of Life Sciences, 11-Minamiooya, Machida-shi, Tokyo 194, Japan;Faculty of Pharmacy, Meijo University, Tempaku, Nagoya 468, Japan |
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| Abstract: | A new bromine-containing alkaloid, keramadine, has been isolated from the Okinawan sea sponge Agelas sp. as a novel antagonist of serotonergic receptors and its structure has been elucidated by n.m.r. spectrometry. |
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