A catalytic asymmetric anti-selective nitroaldol reaction with a neodymium-sodium heterobimetallic complex |
| |
| Authors: | Tatsuya Nitabaru Masakatsu Shibasaki |
| |
| Institution: | Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan |
| |
| Abstract: | A catalytic asymmetric anti-selective nitroaldol reaction with a neodymium-sodium heterobimetallic catalyst is described. A readily accessible amide ligand works efficiently as a chiral platform for the Nd/Na heterobimetallic catalyst in the reaction of various aldehydes and nitroethane, affording anti-1,2-nitro alkanols in good diastereo- and enantioselectivity. |
| |
| Keywords: | Nitroaldol (Henry) reaction Neodymium Heterobimetallic catalyst Asymmetric catalysis |
| 本文献已被 ScienceDirect 等数据库收录！ |
