| 一种新型噻二唑Schiff碱的合成及生物活性研究 |
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| 引用本文： | 陈传兵,伍海涛,王涛,张荣.一种新型噻二唑Schiff碱的合成及生物活性研究[J].广州化学,2010,35(1):38-40,47. |
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| 作者姓名： | 陈传兵 伍海涛 王涛 张荣 |
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| 作者单位： | 1. 广州中医药大学中药学院,广东,广州,510405
2. 广州中医药大学临床药理研究所,广东,广州,510405 |
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| 摘 要： | 为了寻找具有较高植物生长调节活性的物质,利用生物等排原理和亚结构连接法,对噻二唑母体进行修饰,将2-氨基-1,3,4-噻二唑与2,4-二氯苯甲醛反应,设计并合成了一个新的噻二唑席夫碱,并用FT-IR、1HNMR和元素分析方法确证其结构。合成的化合物具有一定的植物生长调节活性,具有一定的研究开发价值。
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| 关 键 词： | 噻二唑席夫碱 合成 植物生长调节活性 |
Synthesis and Biological Activity of One New 1,3,4-Thiodiazole Schiff Base |
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| CHEN Chuan-bing,WU Hai-tao,WANG Tao,ZHANG Rong.Synthesis and Biological Activity of One New 1,3,4-Thiodiazole Schiff Base[J].Guangzhou Chemistry,2010,35(1):38-40,47. |
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| Authors: | CHEN Chuan-bing WU Hai-tao WANG Tao ZHANG Rong |
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| Institution: | 1. College of Traditional Chinese Medicine;Guangzhou University of Chinese Medicine;2. Institute of Clinical Pharmacology;Guangzhou 510405;China |
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| Abstract: | To seek good plant growth regulators, the parent structure of 1,3,4-thiodiazole was modified by bioisosterism principles and Substructure Link Wory. One new thiadiazole Schiff base was synthesized with 2-amino-1,3,4-thiodiazole and 2,4-dichloro benzaldehyde. The structure of thiadiazole Schiff base was confirmed by FT-IR, 1H NMR and elementary analysis. The target compound had plant growth regulating activity and was worth developing. |
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| Keywords: | 1 3 4-thiodiazole Schiff base synthesis plant growth regulating activity |
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