Synthesis and characterization of poly(vinyl alcohol)‐graft‐[poly(D,L‐lactide)/poly(D,L‐lactide‐co‐glycolide)] hydrogels |
| |
| Authors: | Elvira Vidović Doris Klee Hartwig Höcker |
| |
| Affiliation: | 1. Faculty of Chemical Engineering and Technology, University of Zagreb, 10000 Zagreb, Croatia;2. Department of Textile and Macromolecular Chemistry, RWTH Aachen, 52056 Aachen, Germany;3. Department of Textile and Macromolecular Chemistry, RWTH Aachen, 52056 Aachen, GermanyDepartment of Textile and Macromolecular Chemistry, RWTH Aachen, 52056 Aachen, Germany |
| |
| Abstract: | Poly(D ,L ‐lactide) and poly(D ,L ‐lactide‐co‐glycolide) with various composition and with one methacrylate and one carboxylate end group were synthesized and grafted onto poly(vinyl alcohol) (PVA) via the carboxylate group. The graft copolymers were crosslinked via the methacrylate groups using a free radical initiator. The polymer networks were characterized by means of NMR and studied qualitatively by means of IR spectroscopy. The influence of the glycolide content in the polyester grafts and of the number of ester units in the grafts on thermal properties and swellability were studied as well. The high swellability in water is characteristic of all hydrogels. Differential scanning calorimetry (DSC) showed a single glass transition temperature that occurs in the range between 51 and 69 °C. Thermogravimetric analysis (TGA) of the networks showed the main loss in weight in the temperature range between 290 and 370 °C. © 2007 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 45: 4536–4544, 2007 |
| |
| Keywords: | biodegradable hydrogels poly(D,L‐lactide) poly(D,L‐lactide‐co‐glycolide) polyesters poly(vinyl alcohol) swellability synthesis thermal properties thermogravimetric analysis |
|
|
