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Novel method for analyzing proteome
Authors:Bo Liao  Jiawei Luo  Renfa Li  Wen Zhu
Affiliation:1. Laboratory of Embedded Computing and System, School of Computer and Communication, Hunan University, Changsha Hunan, 410082, People's Republic of ChinaLaboratory of Embedded Computing and System, School of Computer and Communication, Hunan University, Changsha Hunan, 410082, People's Republic of China;2. Laboratory of Embedded Computing and System, School of Computer and Communication, Hunan University, Changsha Hunan, 410082, People's Republic of China
Abstract:We propose a 6D representation of protein sequences consisting of 20 amino acids. Based on this 6D representation, we propose a proteome distance measure for constructing phylogenic tree. And we make use of the corresponding similarity matrix to construct phylogenic tree. The examination of phylogenic tree belong to 30 mitochondrial sequence illustrates the utility of our approach. © 2006 Wiley Periodicals, Inc. Int J Quantum Chem, 2007
Keywords:phylogenetic tree  protein sequence  proteome  6D representation
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