Novel method for analyzing proteome |
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Authors: | Bo Liao Jiawei Luo Renfa Li Wen Zhu |
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Affiliation: | 1. Laboratory of Embedded Computing and System, School of Computer and Communication, Hunan University, Changsha Hunan, 410082, People's Republic of ChinaLaboratory of Embedded Computing and System, School of Computer and Communication, Hunan University, Changsha Hunan, 410082, People's Republic of China;2. Laboratory of Embedded Computing and System, School of Computer and Communication, Hunan University, Changsha Hunan, 410082, People's Republic of China |
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Abstract: | We propose a 6D representation of protein sequences consisting of 20 amino acids. Based on this 6D representation, we propose a proteome distance measure for constructing phylogenic tree. And we make use of the corresponding similarity matrix to construct phylogenic tree. The examination of phylogenic tree belong to 30 mitochondrial sequence illustrates the utility of our approach. © 2006 Wiley Periodicals, Inc. Int J Quantum Chem, 2007 |
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Keywords: | phylogenetic tree protein sequence proteome 6D representation |
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