Recent Progress in Boosted PDT Induced Immunogenic Cell Death for Tumor Immunotherapy |
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| Authors: | LI Jun OU Hanlin DING Dan |
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| Institution: | State Key Laboratory of Medicinal Chemical Biology,Key Laboratory of Bioactive Materials,Ministry of Education,College of Life Sciences,Nankai University,Tianjin 300071,P.R.China;State Key Laboratory of Medicinal Chemical Biology,Key Laboratory of Bioactive Materials,Ministry of Education,College of Life Sciences,Nankai University,Tianjin 300071,P.R.China;State Key Laboratory of Medicinal Chemical Biology,Key Laboratory of Bioactive Materials,Ministry of Education,College of Life Sciences,Nankai University,Tianjin 300071,P.R.China |
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| Abstract: | With the rapid development of materials science, photosensitive materials have been widely used in the field of immunogenic cell death(ICD), which was on account of the reactive oxygen species(ROS) generation by photosensitizer under light irradiation inducing cellular oxidative stress during the dying of cells. Considerable researches related to photodynamic therapy(PDT) induced ICD were conducted and exhibited brilliant performance in cancer immunotherapy. Herein, a variety of different strategies for PDT induced ICD have been summarized and discussed to provide researchers more inspiration for cancer immunotherapy. |
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| Keywords: | Photodynamic therapy Immunogenic cell death Damage-associated molecular pattern |
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