| Synthesis of Gibbilimbols A ～ D and Their ( Z )-Isomers |
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| 引用本文： | ZHOU Ling YANG Yong-Gang CAO Xiao-Ping. Synthesis of Gibbilimbols A ～ D and Their ( Z )-Isomers[J]. 有机化学, 2003, 23(Z1): 439-439 |
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| 作者姓名： | ZHOU Ling YANG Yong-Gang CAO Xiao-Ping |
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| 作者单位： | ZHOU Ling（National Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000） YANG Yong-Gang（National Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000） CAO Xiao-Ping（National Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000） |
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| 基金项目： | Project supported by the National Natural Science Foundation of China (QT program No. 20021001 ). |
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| 摘 要： | Gibbilimbols (1) were isolated from the leaves of Piper gibbilimbum in Papua New Guinea, which showed cyto toxicity toward KB nasopharyngal cancer cells (EDs0 2～ 8 μg/mL) and antibacterial activity against Staphylococcus epidermidis and Bacillus cereus (MIC 2 ～4 μg/mL). [1] Only two methods were reported for the synthesis of them,one is a coupling of phenolic part with alkyne, followed by reduction of triple bond by Mori. [2]
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Synthesis of Gibbilimbols A ～ D and Their ( Z )-Isomers |
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| ZHOU Ling,YANG Yong-gang,CAO Xiao-Ping. Synthesis of Gibbilimbols A ～ D and Their ( Z )-Isomers[J]. Chinese Journal of Organic Chemistry, 2003, 23(Z1): 439-439 |
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| Authors: | ZHOU Ling YANG Yong-gang CAO Xiao-Ping |
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| Abstract: | Gibbilimbols (1) were isolated from the leaves of Piper gibbilimbum in Papua New Guinea, which showed cyto toxicity toward KB nasopharyngal cancer cells (EDs0 2～ 8 μg/mL) and antibacterial activity against Staphylococcus epidermidis and Bacillus cereus (MIC 2 ～4 μg/mL). [1] Only two methods were reported for the synthesis of them,one is a coupling of phenolic part with alkyne, followed by reduction of triple bond by Mori. [2] |
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