Three New Benzophenone Glucosides from the Leaves of Planchonella obovata |
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Authors: | Shoei‐Sheng Lee Chang‐Cheng Tseng Chien‐Kuang Chen |
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Institution: | School of Pharmacy, College of Medicine, National Taiwan University, 1, Sec.?1, Jen‐Ai Rd, Taipei 10051, Taiwan, R.O.C. (phone/fax: +886?2?23916127) |
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Abstract: | Chemical investigation of the EtOH extract of the leaves of Planchonella obovata resulted in the isolation of four benzophenone glucosides, 1 – 4 , of which three, 2 – 4 , are new chemical entities together with five known flavonol glycosides. Their structures were elucidated by spectroscopic analysis. Among the isolated compounds, iriflophenone 2‐O‐(2,6‐di‐O‐galloyl)‐β‐D ‐glucopyranoside ( 4 ) showed some activity (91.4 and 15.0% inhibition at 100 and 10 μg/ml, resp.) against the α‐glucosidase of Bacillus stearothermophilus. |
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Keywords: | Planchonella obovata Glycosides α ‐Glucosidase inhibitor Inhibitors Benzophenone glucosides Flavonol glycosides Iriflophenone derivative |
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