First Total Synthesis of Mappain with a Prenylated and Geranylated Stilbene |
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| Authors: | Lakkoju Chakrapani Eun Mi Jung Yong Rok Lee |
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| Affiliation: | 1. School of Chemical Engineering and Technology, Yeungnam University, Gyeongsan 712‐749, Korea, (phone: +82‐53‐810?–?2529;2. fax: +82‐53‐810‐4631) |
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| Abstract: | The first total synthesis of naturally occurring mappain has been achieved by a convergent sequence. The key strategy involved in the synthesis of mappain was a (E)‐stilbene formation by Horner–Wadsworth–Emmons reaction of the corresponding prenylated benzaldehyde with a geranylated benzyl phosphonate. |
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| Keywords: | Mappain Horner – Wadsworth – Emmons reaction Stilbene Benzaldehyde, prenylated Benzyl phosphate, geranylated |
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