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Manganese-catalyzed ring-opening carbonylation of cyclobutanol derivatives
Authors:Tim Meyer  Zhiping Yin  Xiao-Feng Wu
Institution:LIKAT (Leibniz-Institut für Katalyse e.V.), Albert-Einstein-Straße 29a, 18059 Rostock, Germany
Abstract:Herein, we report a manganese-catalyzed ring-opening carbonylation of cyclobutanol derivatives through cyclic C/>C bond cleavage. The reaction happens via a radical-mediated pathway to selectively generate 1,5-ketoesters. A variety of substrates with substituents on the aromatic ring reacted with linear alcohols of different chain lengths. Obtained aliphatic esters are very attractive since they are usually difficult to access.</td>
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Keywords:Carbonylation  Ring-opening  Manganese  1  5-Ketoesters
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