Oxygenated 4‐Methylidene Sterols from the South China Sea Sponge Theonella swinhoei |
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| Authors: | Hong‐Jun Zhang Yang‐Hua Yi Hou‐Wen Lin |
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| Institution: | 1. Laboratory of Marine Drugs, Department of Pharmacy, Changzheng Hospital, Second Military Medical University, 415 Fengyang Road, Shanghai 200003, P.?R. China, (phone/fax: +86‐21‐65585154);2. Research Center for Marine Drugs, School of Pharmacy, Second Military Medical University, 325 Guohe Road, Shanghai 200433, P.?R. China, (phone: +86‐21‐65384988;3. fax: +86‐21‐65483662);4. Hospital of PLA Troops 95746, Qionglai 611531, P.?R. China |
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| Abstract: | Two new O‐bearing 4‐methylidene sterols, 9α‐hydroxy‐15‐oxoconicasterol ( 1 ) and 8β‐hydroxy‐B‐norconicasta‐6α‐aldehyde ( 2 ), were isolated from the EtOH extract of the marine sponge Theonella swinhoei collected from the South China Sea. Their structures were elucidated by spectroscopic data and comparison with known compounds. In addition, spectroscopic data reported for the known 4‐methylidene sterol 7α‐hydroxyconicasterol ( 3 ) were revised. |
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| Keywords: | Theonella swinhoei Sterols 4‐methylidene‐ Sponges |
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