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Daphnane‐Type Diterpenoids from the Flower Buds of Daphne genkwa
Authors:Ling‐Zhi Li  Pin‐Yi Gao  Ying Peng  Li‐Hui Wang  Jing‐Yu Yang  Chun‐Fu Wu  Yan Zhang  Shao‐Jiang Song
Institution:1. School of Traditional Chinese Materia Medica, Key Laboratory of Structure‐Based Drug Design &, Discovery, Shenyang Pharmaceutical University, Shenyang 110016, P.?R. China , (phone: +86‐24‐23986510);2. School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, P.?R. China
Abstract:Three new daphnane‐type diterpenoids, genkwanines M–O ( 1 – 3 , resp.), together with seven known daphnane‐type diterpenoids, genkwanines D and H, genkwaine F, genkwadaphnine, yuanhuatine, yuanhuafine, and yuanhuapine ( 4 – 10 , resp.), were isolated from the flower buds of Daphne genkwa during a phytochemical investigation. The structures of the new compounds were elucidated on the basis of spectroscopic analyses, especially 2D‐NMR spectra (HSQC, HMBC, and NOESY).
Keywords:Daphne genkwa  Daphnane‐type diterpenoids  Diterpenoids  Genkwanines M       O
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