Daphnane‐Type Diterpenoids from the Flower Buds of Daphne genkwa |
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Authors: | Ling‐Zhi Li Pin‐Yi Gao Ying Peng Li‐Hui Wang Jing‐Yu Yang Chun‐Fu Wu Yan Zhang Shao‐Jiang Song |
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Institution: | 1. School of Traditional Chinese Materia Medica, Key Laboratory of Structure‐Based Drug Design &, Discovery, Shenyang Pharmaceutical University, Shenyang 110016, P.?R. China , (phone: +86‐24‐23986510);2. School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, P.?R. China |
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Abstract: | Three new daphnane‐type diterpenoids, genkwanines M–O ( 1 – 3 , resp.), together with seven known daphnane‐type diterpenoids, genkwanines D and H, genkwaine F, genkwadaphnine, yuanhuatine, yuanhuafine, and yuanhuapine ( 4 – 10 , resp.), were isolated from the flower buds of Daphne genkwa during a phytochemical investigation. The structures of the new compounds were elucidated on the basis of spectroscopic analyses, especially 2D‐NMR spectra (HSQC, HMBC, and NOESY). |
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Keywords: | Daphne genkwa Daphnane‐type diterpenoids Diterpenoids Genkwanines M – O |
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