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Biological Effects of Black Phosphorus Nanomaterials on Mammalian Cells and Animals |
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| Authors: | Prof. Xuejiao Zhang Dr. Ievgen S. Donskyi Dr. Weihao Tang Shuo Deng Daxu Liu Prof. Siyu Zhang Prof. Qing Zhao Prof. Baoshan Xing |
| Affiliation: | 1. National–Regional Joint Engineering Research Center for Soil Pollution Control and Remediation in South China, Guangdong Key Laboratory of Integrated Agro-environmental Pollution Control and Management, Institute of Eco-environmental and Soil Sciences, Guangdong Academy of Sciences, Guangzhou, 510650 China;2. Institut für Chemie und Biochemie, Freie Universität Berlin, Takustrasse 3, 14195 Berlin, Germany;3. Key Laboratory of Pollution Ecology and Environmental Engineering, Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang, 110016 China University of Chinese Academy of Sciences, Beijing, 100049 China;4. Key Laboratory of Pollution Ecology and Environmental Engineering, Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang, 110016 China;5. Stockbridge School of Agriculture, University of Massachusetts, Amherst, MA 01003 USA |
| Abstract: | The remarkable progress of applied black phosphorus nanomaterials (BPNMs) is attributed to BP's outstanding properties. Due to its potential for applications, environmental release and subsequent human exposure are virtually inevitable. Therefore, how BPNMs impact biological systems and human health needs to be considered. In this comprehensive Minireview, the most recent advancements in understanding the mechanisms and regulation factors of BPNMs’ endogenous toxicity to mammalian systems are presented. These achievements lay the groundwork for an understanding of its biological effects, aimed towards establishing regulatory principles to minimize the adverse health impacts. |
| Keywords: | Biological Effects Black Phosphorus Nanomaterials Environmental Exposure Intrinsic Chemical Activity Toxicity Mechanism |