| Electrochemical reduction process of bilirubin in dimethylformamide |
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| 作者姓名： | NIU Jian-Jun DONG Shao-JunLaboratory of Electroanalytical Chemistry Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun Jilin China |
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| 作者单位： | NIU，Jian-Jun DONG，Shao-JunLaboratory of Electroanalytical Chemistry，Changchun Institute of Applied Chemistry，Chinese Academy of Sciences，Changchun，Jilin 130022，China |
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| 基金项目： | Project supported by the National Natural Science Foundation of China. |
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| 摘 要： | The electrochemical reduction behavior of bilirubin (BR) at platinum electrode in DMF was investigated by cyclic voltammetry, in situ electron spin resonance spectroscopy and in situ rapid scanning thin layer spectroelectrochemistry. Experimental results revealed that thereduction of BR firstly undergoes an ECE process: BR-+e BR-dimerize (BR)22- +e(BR)23-. The generated (BR)23- can be re-oxidized to BR and then to purpurin (Pu) by a series of oxidation processes:(BR)23- -e (BR)22- -2e 2BR, BR --2e BV --2e Pu. However, the re-reduction reactions of Pu are not the reverse processes. The different reduction mechanisms are discussed in detail.
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Electrochemical reduction process of bilirubin in dimethylformamide |
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| NIU,Jian-Jun DONG,Shao-JunLaboratory of Electroanalytical Chemistry,Changchun Institute of Applied Chemistry,Chinese Academy of Sciences,Changchun,Jilin ,China.Electrochemical reduction process of bilirubin in dimethylformamide[J].Chinese Journal of Chemistry,1995,13(4):289-298. |
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| Authors: | NIU Jian-Jun DONG Shao-JunLaboratory of Electroanalytical Chemistry Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun Jilin China |
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| Institution: | NIU,Jian-Jun DONG,Shao-JunLaboratory of Electroanalytical Chemistry,Changchun Institute of Applied Chemistry,Chinese Academy of Sciences,Changchun,Jilin 130022,China |
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| Abstract: | The electrochemical reduction behavior of bilirubin (BR) at platinum electrode in DMF was investigated by cyclic voltammetry, in situ electron spin resonance spectroscopy and in situ rapid scanning thin layer spectroelectrochemistry. Experimental results revealed that thereduction of BR firstly undergoes an ECE process: BR-+e BR-dimerize (BR)22- +e(BR)23-. The generated (BR)23- can be re-oxidized to BR and then to purpurin (Pu) by a series of oxidation processes:(BR)23- -e (BR)22- -2e 2BR, BR --2e BV --2e Pu. However, the re-reduction reactions of Pu are not the reverse processes. The different reduction mechanisms are discussed in detail. |
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| Keywords: | Bilirubin biliverdin purpurin spectroelectrochemistry bioelectrochemistry |
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