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Qualitative analysis of a time‐delayed free boundary problem for tumor growth under the action of external inhibitors
Authors:Shihe Xu  Qinghua Zhou  Meng Bai
Institution:School of Mathematics and Statistics, Zhaoqing University, Zhaoqing, Guangdong 526061, China
Abstract:In this paper, a time‐delayed free boundary problem for tumor growth under the action of external inhibitors is studied. It is assumed that the process of proliferation is delayed compared with apoptosis. By Lp theory of parabolic equations, the Banach fixed point theorem and the continuation theorem, the existence and uniqueness of a global solution is proved. The asymptotic behavior of the solution is also studied. The proof uses the comparison principle and the iteration method. Copyright © 2014 John Wiley & Sons, Ltd.
Keywords:tumor growth  inhibitors  time delay  existence and uniqueness  asymptotic behavior  subclass35K57  35Q92  39B12
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