Qualitative analysis of a time‐delayed free boundary problem for tumor growth under the action of external inhibitors |
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Authors: | Shihe Xu Qinghua Zhou Meng Bai |
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Institution: | School of Mathematics and Statistics, Zhaoqing University, Zhaoqing, Guangdong 526061, China |
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Abstract: | In this paper, a time‐delayed free boundary problem for tumor growth under the action of external inhibitors is studied. It is assumed that the process of proliferation is delayed compared with apoptosis. By Lp theory of parabolic equations, the Banach fixed point theorem and the continuation theorem, the existence and uniqueness of a global solution is proved. The asymptotic behavior of the solution is also studied. The proof uses the comparison principle and the iteration method. Copyright © 2014 John Wiley & Sons, Ltd. |
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Keywords: | tumor growth inhibitors time delay existence and uniqueness asymptotic behavior subclass35K57 35Q92 39B12 |
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