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Photocytotoxicity of platinum(IV)-chloride surface modified TiO2 irradiated with visible light against murine macrophages |
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| Authors: | Jańczyk Agnieszka Wolnicka-Głubisz Agnieszka Urbanska Krystyna Stochel Grazyna Macyk Wojciech |
| Institution: | Faculty of Chemistry, Jagiellonian University, Ingardena 3, 30-060 Kraków, Poland. |
| Abstract: | Phototoxicity of titanium dioxide modified with platinum(IV)-chloride complexes, TiO2/PtCl4], irradiated with visible light was tested on murine macrophage cell line (RAW 264.7) in vitro. Presence of antioxidants such as alpha-tocopherol or beta-carotene during photodynamic treatment significantly increased cells viability. Our results indicate that observed cell death induced by TiO2/PtCl4] was due to photogeneration of reactive species. |
| Keywords: | Reactive oxygen species Titanium dioxide Photocatalysis Phototoxicity Murine macrophages |
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