| 2-取代苯并噻唑化合物的合成进展 |
| |
| 引用本文： | 张俊,刘雅菲,张育榕,呼亮,韩世清.2-取代苯并噻唑化合物的合成进展[J].有机化学,2021(3):1053-1071. |
| |
| 作者姓名： | 张俊 刘雅菲 张育榕 呼亮 韩世清 |
| |
| 作者单位： | 南京工业大学生物与制药工程学院 |
| |
| 基金项目： | 国家重大创新药物科技计划基金(No.2017ZX09101002-001-004);江苏省研究生科研与实践创新计划(No.SJCX200410)资助项目。 |
| |
| 摘 要： | 2-取代苯并噻唑在生物医药、材料科学等领域的应用和研究使其合成方法受到了广泛的关注.在传统合成方法的研究基础之上,单质硫介导的氧化还原反应和饱和化合物的脱氢芳构化反应等新方法的发展,为苯并噻唑衍生物的合成提供更多可能.此外,近年来新型金属-有机骨架催化剂、组合离子液体/凝胶、超声以及微波辅助等的应用,极大地丰富了苯并噻...
|
| 关 键 词： | 2-取代苯并噻唑 缩合 脱氢 氧化还原 芳基化 偶联环化 |
Progress in Synthesis of 2-Substituted Benzothiazole Compounds |
| |
| Jun Zhang,Yafei Liu,Yurong Zhang,Liang Hu,Shiqing Han.Progress in Synthesis of 2-Substituted Benzothiazole Compounds[J].Chinese Journal of Organic Chemistry,2021(3):1053-1071. |
| |
| Authors: | Jun Zhang Yafei Liu Yurong Zhang Liang Hu Shiqing Han |
| |
| Institution: | (College of Biotechnology and Pharmaceutical Engineering,Nanjing Tech University,Nanjing 211816) |
| |
| Abstract: | The application and research of 2-substituted benzothiazoles in biomedicine, materials science and other fields have made their synthetic methods widely concerned. Based on the research of traditional synthetic methods, the development of new methods such as elemental sulfur-mediated redox reaction and dehydroaromatization of saturated compounds could provide more possibilities for the synthesis of benzothiazole derivatives. In addition, the application of new metal-organic framework catalysts, combined ionic liquids/gels, ultrasound and microwave assist in recent years have greatly enriched the synthesis of benzothiazole derivatives. The synthetic method of 2-substituted benzothiazoles in recent years is analyzed. |
| |
| Keywords: | 2-substituted benzothiazole condensation dehydrogenation redox arylation coupling cyclization |
| 本文献已被 CNKI 维普 等数据库收录！ |
