Microfabricated porous glass channels for electrokinetic separation devices |
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Authors: | Cezar de Andrade Costa Reges Mogensen Klaus Bo Kutter Jörg Peter |
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Institution: | MIC-Department of Micro and Nanotechnology, Technical University of Denmark, 2800 Kgs Lyngby, Denmark. |
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Abstract: | Electrically insulated porous SiO2 channels for electrokinetic separation devices were fabricated based on a mask-less etching process for creation of high aspect ratio needles in silicon. The silicon needles are converted to SiO2 by oxidation and integrated within the interior of a fluidic channel network. The channels are about 5 microm high with a pore size of 0.5+/-0.2 microm. An electrophoretic separation of a mixture of fluorescein and 5-carboxyfluorescein using epi-fluorescence detection was performed to verify proper electrokinetic transport in the porous channels. The plate height was about 170,000 m-1 for a field strength of 170 V cm-1. In the near future, it is intended to extend the fabrication scheme to include an array of porous pillars for capillary electrochromatography experiments. |
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