| 一锅法有效合成氨基甲酸酯类化合物 |
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| 引用本文： | 李立清,王晓刚,郭三霞,刘重洋,何益波.一锅法有效合成氨基甲酸酯类化合物[J].有机化学,2007,27(4):519-523. |
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| 作者姓名： | 李立清 王晓刚 郭三霞 刘重洋 何益波 |
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| 作者单位： | 1. 中南大学能源科学与工程学院 长沙 410083
2. 湖南大学环境科学与工程学院,长沙,410082 |
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| 基金项目： | 国家自然科学基金（Nos.20376019,20576028）资助项目. |
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| 摘 要： | 以四甲基胍(TMG)为催化剂, 乙腈(ACT)为溶剂, 利用CO2、胺和烷基氯三组分在0.10 MPa, 70～80 ℃条件下, 一锅法有效合成氨基甲酸酯类化合物, 并研究了收率和产率的影响. 结果表明, 最优反应条件为n(胺)∶n(烷基氯)＝3～4、反应温度70～80 ℃、反应时间2～3 h、酯分离收率达68.7%～81.3%, 酯纯度达到99.9%
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| 关 键 词： | 氨基甲酸酯 CO2 亲核取代反应 位阻效应 |
| 收稿时间： | 2006-6-5 |
| 修稿时间： | 2006-06-05 |
One-Pot Synthesis of Carbamate |
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| LI,Li-Qing,WANG,Xiao-Gang,GUO,San-Xia,LIU,Chong-Yang,HE,Yi-Bo.One-Pot Synthesis of Carbamate[J].Chinese Journal of Organic Chemistry,2007,27(4):519-523. |
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| Authors: | LI Li-Qing WANG Xiao-Gang GUO San-Xia LIU Chong-Yang HE Yi-Bo |
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| Institution: | a .School of Energy Science and Engineering, Central South University, Changsha 410083;b. College of Environmental Science and Engineering, Hunan University, Changsha 410082 |
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| Abstract: | Carbamates were prepared by one-pot synthesis from carbon dioxide, amine and alkyl chloride with N,N,N,N-tetramethyl guanidine (TMG) as catalyst, acetonitrile (ACT) as solvents at a pressure of 0.10 MPa and temperature of 70～80 ℃. Effects of the converting ratio and yield were investigated. The results showed that the optimum technological conditions should be that n(amine)∶n(alkyl chloride)＝3～4, the reaction temperature was 70～80 ℃, and reaction time was 2～3 h. The purity of the refined of carbamates was 99.9%, and the yield of carbamates was in the range of 68.7%～81.3%. |
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| Keywords: | CO2 |
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