| 微量元素与老年性痴呆 |
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| 引用本文： | 罗超,周江宁,刘桂建,彭子成. 微量元素与老年性痴呆[J]. 广东微量元素科学, 2004, 11(7): 1-6 |
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| 作者姓名： | 罗超 周江宁 刘桂建 彭子成 |
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| 作者单位： | 1. 中国科学技术大学地球和空间科学学院,安徽,合肥,230026
2. 中国科学技术大学生命科学学院,安徽,合肥,230026 |
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| 基金项目： | 中国科学院知识创新工程项目 (KZCX2 SW 118,KZCX SW 12 0 )，国家科技部基础研究重大项目(2 0 0 1CCB0 0 10 0 )资助 |
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| 摘 要： | 阐明了几种微量元素在人体内某些部位的含量变化及其对神经系统产生的影响 ,以及与阿尔茨海默病 (老年性痴呆病 ,AD)临床症状的关系。研究表明 ,一些AD发病机制诸如突触及神经元的丢失、细胞内神经原的缠结和细胞外的老年斑等 ,与病人体内某些微量元素含量的异常密切相关 ,而且影响机制复杂 ,途径多样。探明微量元素的作用机制 ,对AD病的防治和诊断意义重大
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| 关 键 词： | 阿尔茨海默病 微量元素 神经 大脑皮层 |
| 文章编号： | 1006-446X(2004)07-0001-06 |
| 修稿时间： | 2004-04-10 |
The Relationship between Several Trace Elements and Alzheimer''''s Disease |
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| LUO Chao ,ZHOU Jiang-ning ,LIU Gui-jian ,PENG Zi-cheng. The Relationship between Several Trace Elements and Alzheimer''''s Disease[J]. Trace Elements Science, 2004, 11(7): 1-6 |
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| Authors: | LUO Chao ZHOU Jiang-ning LIU Gui-jian PENG Zi-cheng |
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| Affiliation: | LUO Chao 1,ZHOU Jiang-ning 2,LIU Gui-jian 1,PENG Zi-cheng 1 |
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| Abstract: | A review with 25 references is given on the relationship between several trace elements and Alzheimer's disease including the change of the concentration of several trace elements in some parts of the body,and how this change influences nervous system,what happened in the process,and those questions that still needs to further investigate.Moreover try to find out some new ways in situ to detect the concentration of the element.The conclusion is that some mechanism of Alzheimer's disease,for example,neurofibrillary tangles and senile plaques,are concerned with the abnormity of the concentration of several trace elements in some parts of the body,the mechanism is very complex and there are many ways to conduce the occurrence of the disease. |
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| Keywords: | Alzheimer's disease nerve pallium trace element |
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