a Molecular Innovation, Diversity and Automated Synthesis (MIDAS) Centre, School of Chemistry, Leeds University, Leeds LS2 9JT, UK b Avecia Lifesciences Molecules, PO Box 521, Leeds Road, Huddersfield HD2 1GA, UK
Abstract:
The Pd/Cu-catalysed cross-coupling reaction of heterocyclic terminal alkynes and allene/allenyl heterocycles affords novel trisubstituted en-ynes in good yield.