Novel chiral ferrocenyl-imino phosphine ligands and their use in palladium catalyzed allylic alkylations |
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| Authors: | Pierluigi Barbaro Claudio BianchiniGiuliano Giambastiani Antonio Togni |
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| Affiliation: | a Istituto di Chimica dei Composti Organo Metallici (ICCOM-CNR), Florence Research Area, Via Madonna del Piano, 50019-Sesto Fiorentino-Firenze, Italy
b Department of Chemistry, Swiss Federal Institute of Technology, ETH Hönggerberg, CH-8093 Zürich, Switzerland |
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| Abstract: | New chiral P,N-ferrocenyl imino-phosphine ligands have been synthesized and the absolute configuration of the stereocenters in each molecule has been determined by a single-crystal X-ray analysis of a common intermediate. PdII-allyl complexes of the new ligands have been isolated and tested as catalyst precursors in the asymmetric allylic alkylation of 1,3-diphenylprop-2-en-1-yl acetate with dimethyl malonate in different solvents. Quantitative yields and enantiomeric excesses as high as 80% have been obtained. |
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| Keywords: | chiral ligands ferrocenes imino-phosphines asymmetric catalysis |
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