Macrodasine A, a novel macroline derivative incorporating fused spirocyclic tetrahydrofuran rings containing a spiroacetal moiety |
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Authors: | Toh-Seok Kam Yeun-Mun Choo |
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Institution: | Department of Chemistry, University of Malaya, 50603 Kuala Lumpur, Malaysia |
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Abstract: | A novel indole alkaloid, viz., macrodasine A, incorporating fused spirocyclic tetrahydrofuran rings onto a macroline-like moiety, was obtained from a Malayan Alstonia species. The structure, which is also notable for the presence of an unprecedented spiroacetal moiety in an indole alkaloid, was established by spectroscopic analysis. |
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Keywords: | alkaloids indoles NMR plants |
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