Highly enantioselective synthesis of 2,3-dihydroquinazolinones through intramolecular amidation of imines |
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| Authors: | Prakash Muthuraj Kesavan Venkitasamy |
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| Affiliation: | Department of Biotechnology, Bhupat and Jyothi Mehta School of Biosciences Building, Indian Institute of Technology Madras, Chennai 600036, India. |
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| Abstract: | Enantioselective synthesis of 2,3-dihydroquinazolinones (DHQZs) was accomplished using readily available Sc(III)-inda-pybox as the catalyst. This is the first report on the metal catalyzed asymmetric intramolecular amidation of imines to synthesize DHQZs. |
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