Suzuki coupling for protein modification |
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Authors: | Akio Ojida |
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Affiliation: | PRESTO (Synthesis and Control, JST), Institute for Materials Chemistry and Engineering (IMCE), Kyushu University, Hakozaki, Fukuoka 812-8581, Japan |
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Abstract: | Suzuki-coupling, a representative cross-coupling reaction between small molecules, can proceed on a protein surface in aqueous solution under mild conditions. The modified protein produced by the coupling reaction maintained its native like structure and function. In addition, fluorescent dye appended-protein acts as a fluorescent biosensor. |
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Keywords: | Suzuki coupling Protein Modification Fluorescent biosensor |
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