Novel rearrangement of 7-(substituted aminomethyl)-6,7-dihydrooxazolo[2,3-f]purines to 7-(substituted amino)-7,8-dihydro-6H-[1,3]oxazino[2,3-f]purines |
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| Authors: | Marek T Ceg?a Joanna Potaczek Lucjan Strekowski |
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| Institution: | a Jagiellonian University Medical College, Faculty of Pharmacy, Department of Organic Chemistry, Medyczna 9, PL 30-688 Kraków, Poland
b Department of Chemistry, Georgia State University, Atlanta, GA 30302-4098, USA |
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| Abstract: | Oxazinopurines were obtained in high yield by the reaction of 8-bromotheophylline with morpholinomethyl-, piperidinomethyl- or indolinomethyl-substituted oxiranes without isolation of the intermediate oxazolo2,3-f]purine. |
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| Keywords: | 6 7-Dihydrooxazolo[2 3-f]purine-2 4(1H 3H)-dione Rearrangement 6 7-Dihydro[2 3-f]purine-2 4(1H 3H)-dione |
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