A convenient protocol for C-H oxidation mediated by an azido radical culminating in Ritter-type amidation |
| |
| Authors: | Vijay Nair T.D. Suja Kishor Mohanan |
| |
| Affiliation: | Organic Chemistry Division, Regional Research Laboratory (CSIR), Trivandrum 695 019, India |
| |
| Abstract: | Cerium(IV) ammonium nitrate in combination with sodium azide reacts with unactivated hydrocarbons in acetonitrile to furnish acetamides in one pot. The strategy can be used to introduce nitrogen functionality into a variety of compounds; a carboxylic ester directly afforded the corresponding α-amino acid. |
| |
| Keywords: | Cerium ammonium nitrate CH activation Ritter reaction Azides Radicals |
| 本文献已被 ScienceDirect 等数据库收录！ |
