Efficient access to functionalised medium-ring systems by radical fragmentation/radical addition to α-iodoketones |
| |
| Authors: | Corinne De Dobbeleer |
| |
| Institution: | Université catholique de Louvain, Département de Chimie, Bâtiment Lavoisier Place Louis Pasteur 1, B-1348 Louvain-la-Neuve, Belgium |
| |
| Abstract: | Functionalised medium-ring systems of various sizes can be efficiently prepared by a novel approach that embodies a radical-induced fragmentation of bicyclic β-hydroxy ketones, followed by a second radical-coupling reaction. The unexpected reactivity of α-keto radicals is also discussed. |
| |
| Keywords: | Medium-sized ring Radical fragmentation Intermolecular radical reaction α-Ketoradicals Orthoesters α-Iodoketones |
| 本文献已被 ScienceDirect 等数据库收录！ |
