|
|||||
|
|
Preparation of 2,3-diaminopropionate from ring opening of aziridine-2-carboxylate |
|
| Authors: | Yongeun Kim Kyusung Han Hoseop Yun Min Sung Kim |
| Institution: | a Department of Chemistry, Hankuk University of Foreign Studies, Yongin 449-791, Korea b Imagene Co. Ltd, Biotechnology Incubating Center, Seoul National University, Seoul 151-742, South Korea c Department of Molecular Science and Technology, Ajou University, Suwon 442-749, South Korea d Department of Chemistry, Sogang University, Seoul 121-742, South Korea |
| Abstract: | Ring opening reaction of an enantiomerically pure aziridine-2-carboxylate with an azide nucleophile under aqueous acidic media proceeded efficiently and stereoselectively to give 3-amino-2-azidopropionate which is converted to orthogonally protected 2,3-diaminopropionate. |
| Keywords: | Ring opening Azide Aziridine-2-carboxylate 2 3-Diaminopropionate |
| 本文献已被 ScienceDirect 等数据库收录！ | |