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A new cytotoxic bufadienolide from Chinese medicine Chansu
Authors:Xiu Lan Xin  Rong Lan  Jian Huang  Xiao Jie Wang  Jing Ming Jia  
Institution:a School of Traditional Chinese Medicines, Shenyang Pharmaceutical University, Shengyang 110016, China;b Beijing Vocational College of Electronic Science and Technology, Beijing 100029, China
Abstract:A new cytotoxic bufadienolide was isolated from the traditional Chinese medicine-Chansu. The structure of new compound was elucidated on the basis of spectral methods including 2D NMR. And it showed strong in vitro eytotoxic activity against Hela cells with IC5o of 8.06×10-2 μmol/L.
Keywords:Bufadienolide  Steroid  Cytotoxicity  Chansu
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