Development of a library of 6-arylcoumarins as candidate fluorescent sensors |
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| Authors: | Hirano Tomoya Hiromoto Kenichi Kagechika Hiroyuki |
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| Affiliation: | School of Biomedical Science, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Tokyo, Japan. hiraomc@tmd.ac.jp |
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| Abstract: | [structure: see text]. A bromocoumarin scaffold (1) was reacted with various boronic acid derivatives (2a-l) to afford a library of 6-arylcoumarins (3a-l). This library was found to contain candidate fluorescent sensors for peptidase activity and for nitric oxide. |
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