Carbon nanotubes as potential material for drug delivery—experiment and simulation |
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| Authors: | Artur P Terzyk Marek Wiśniewski Katarzyna Dulska Agnieszka Bielicka Piotr A Gauden Sylwester Furmaniak Karolina Werengowska-Ciećwierz |
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| Institution: | 1. Department of Chemistry, Physicochemistry of Carbon Materials Research Group, N. Copernicus University, Gagarin Street 7, 87-100, Toruń, Poland
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| Abstract: | We discuss the factors influencing the properties of new drug delivery system, composed of carbon nanotubes and analgesic antipyretic drug—paracetamol. Basing on experimental data it is shown, that by a simple manipulation with the heating time at the stage of system preparation, one can easily change the rate of the drug delivery. Moreover, this rate can be changed in a very wide range. Finally, using Molecular Dynamics simulation we also discuss the orientation and properties of drug molecules at different stages of the hot melt deposition process. |
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