The first direct C-H arylation of purine nucleosides |
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Authors: | Cerna Igor Pohl Radek Hocek Michal |
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Affiliation: | Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Gilead & IOCB Research Center, Flemingovo nam. 2, CZ-16610 Prague 6, Czech Republic. |
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Abstract: | Pd-catalyzed direct C-H arylation of unprotected purine nucleosides with aryl iodides at position 8 was developed to allow a straightforward single-step introduction of diverse aryl groups. |
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