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The first direct C-H arylation of purine nucleosides
Authors:Cerna Igor  Pohl Radek  Hocek Michal
Affiliation:Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Gilead & IOCB Research Center, Flemingovo nam. 2, CZ-16610 Prague 6, Czech Republic.
Abstract:Pd-catalyzed direct C-H arylation of unprotected purine nucleosides with aryl iodides at position 8 was developed to allow a straightforward single-step introduction of diverse aryl groups.
Keywords:
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