Short synthesis of bis-NHC-Pd catalyst derived from caffeine and its applications to Suzuki, Heck, and Sonogashira reactions in aqueous solution |
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| Authors: | Fen-Tair Luo Hung-Kun Lo |
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| Affiliation: | Institute of Chemistry, Academia Sinica, Nankang, Taipei 11529, Taiwan, ROC |
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| Abstract: | A short and efficient synthesis of a bis-NHC-palladium catalyst simply prepared from caffeine in two steps was reported. The air and moisture stable Pd catalyst can be used as a good catalyst in running Suzuki-Miyaura, Mizoroki-Heck, and Sonogashira reactions in aqueous solution. |
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| Keywords: | Suzuki reaction Heck reaction Sonogashira reaction bis-NHC-Pd complex Caffeine NHC |
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