Synthesis of novel ferrocenyl-containing pyrazolo[4,3-c]quinolines |
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| Authors: | Gü nseli Turgut Cin,Seda Demirel |
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| Affiliation: | Department of Chemistry, Faculty of Art and Sciences, Akdeniz University, Antalya, Turkey |
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| Abstract: | Synthesis of novel ferrocenyl-substituted pyrazolo[4,3-c]quinolines via the Pictet-Spengler reaction is reported. Iminium intermediate formed by the condensation of pyrazole-based arylamine substrates with ferrocenecarboxaldehyde in acidic medium, undergoes 6-endo cyclization with sufficiently reactive aromatic moiety to form a pyrazolo[4,3-c]quinoline ring. |
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| Keywords: | Ferrocene Pyrazolo[4,3-c]quinoline Pyrazole Quinoline Pictet-Spengler reaction Cyclization |
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